For the treatment of systemic candidiasis (candidemia, visceral candidiasis chronic generalized (granulomatous) candidiasis) loading dose on day 1 of treatment is 12 mg / kg / day on subsequent days is administered at stanozolol tablets.
in cryptococcal infection, including cryptococcal meningitis, loading dose on day 1 of treatment is 12 mg / kg / day, administered in the following days at the rate of 6 mg / kg / day. Depending on the clinical response, the dose may be increased to 12 mg / kg / day. Duration of therapy -. 8-12 weeks
Patients with severe oropharyngeal candidiasis, Candida esophagitis, and the impossibility of oral fluconazole forms administered at the rate of 6 mg / kg – in the first day of therapy in the following days, 3 mg / kg / day.
Duration of treatment for oropharyngeal candidiasis – 2 weeks; When Candida esophagitis -. 3 weeks, continue taking fluconazole another 2 weeks after the relief of symptoms of infection
, for which the risk of infection development associated with the induced neutropenia (patients undergoing bone marrow transplantation for treatment with cytostatic and radiation therapy of malignant For the prevention of fungal infections in children neoplasms) dosestanozolol tablets is 3-12 mg / kg / day, depending on the severity and duration of neutropenia save. . Required to monitor patterns of peripheral blood of newborns under the age of 4 weeks is used in the same doses as in older children, but increase the interval between administration of the drug: from 0 to 2 weeks of age are administered every 72 hours, with 2 4 weeks of life – every 48 hours.
The method of administration
Administered intravenously at a slow infusion mode; infusion rate – 200 mg (1 bottle) per hour. Do not use solution as an infusion environment for the introduction of other drugs.
Fluconazole is generally well tolerated. It is noted that the frequency of adverse drug reactions significantly higher in the population of patients . From the nervous system : headache, dizziness, convulsions. On stanozolol tablets the part of the gastrointestinal tract : changes in taste, nausea, vomiting, diarrhea, flatulence, abdominal pain, dysfunction liver (increased levels of alkaline phosphatase, bilirubin, serum levels of transaminases, hepatitis, hepatocellular necrosis, including fatalities). since the cardiovascular system : prolongation of the interval, flicker / ventricular flutter. from the side of hematopoiesis : thrombocytopenia, leukopenia, neutropenia, agranulocytosis. From the urinary system : renal failure. Allergic reactions : skin rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, anaphylactoid reactions. Other : renal failure, alopecia, hypercholesterolemia, hypertriglyceridemia, hypokalemia.
Overdose Symptoms : transient mental disorders stanozolol tablets – hallucinations, psychosis-reaction (paronoidalnoe behavior); . neurological disorders – ptosis, lacrimation, salivation, disturbances of the dynamics, convulsions, spontaneous urination, dyspnea Treatment : In acute poisoning shows hemodialysis; 3-hour hemodialysis procedure can be reduced serum concentrations of fluconazole by 50%.